Ibicuruzwa

Benzyl N - ({hexahydro-1H-pyrrolizin-7a-yl} methyl) karbamate hydrochloride ni imiti ivanga imiti ishobora gukoreshwa mubijyanye n'ubuvuzi n'ubushakashatsi mu bya farumasi.Igizwe nitsinda rya benzyl ryometse kumikorere ya karbamate, nayo ihuzwa na hexahydro-1H-pyrrolizin-7a-ylmethyl moiety.Kwiyongera kwa hydrochloride mukigo byerekana ko hariho ion ya chloride, yongerera imbaraga mumazi.Iyi nteruro irashobora gukoreshwa inshuro nyinshi kubera imiterere yayo.Carbamates, muri rusange, izwiho kwerekana ibikorwa bitandukanye byibinyabuzima, harimo anticonvulsant, anticancer, na antihypertensive.Kubaho kwitsinda rya benzyl muri benzyl N - ({hexahydro-1H-pyrrolizin-7a-yl} methyl) karbamate hydrochloride irashobora gutanga lipofilique nziza, bigatuma ishobora kwambuka byoroshye.Ibi birashobora kugirira akamaro itangwa ryibiyobyabwenge no kunoza bioavailable.Hexahydro-1H-pyrrolizin-7a-ylmethyl moiety, izwi kandi nka piperidinyl moiety, ikunze kuboneka mubintu bioactive.Piperidine izwiho uruhare nk'imisemburo ya enzyme, modulator ya neurotransmitter, hamwe na anti-inflammatory.Kwinjiza iyi myiyerekano mu kigo bishobora kongera ibikorwa by’ibinyabuzima hamwe n’ubushobozi bwo kuvura.Nubwo kubura amakuru yihariye yerekeranye n’imikoreshereze y’igeragezwa cyangwa ivuriro, ibishoboka birashobora gutekerezwa hashingiwe kumiterere izwi yitsinda ryayo.Benzyl N -.Irashobora kandi gukoreshwa nkigice cyo kubaka cyangwa hagati muguhuza ibindi binyabuzima bioaktique.Ni ngombwa kumenya ko mbere yubushakashatsi ubwo aribwo bwose cyangwa iperereza rindi, ubushakashatsi bunoze nubushakashatsi burimo ubushakashatsi bwuburozi, kuvura imiti ya chimique, no gusuzuma intego runaka. bigomba gukorwa.Ibi bizafasha kumenya umutekano, imikorere, nuburyo bunoze bwibikorwa bya benzyl N - ({hexahydro-1H-pyrrolizin-7a-yl} methyl) karbamate hydrochloride, amaherezo biganisha ku gukoreshwa mu rwego rwubuvuzi.