Ibicuruzwa

Umubyibuho ukabije, diyabete yo mu bwoko bwa 2 na hyperlipidemiya bikunze kubana kandi bifitanye isano no kwiyongera cyane kw'indwara n'impfu.Kunywa karubone nziza cyane na fructose byiyongereye cyane mumyaka yashize kandi byagereranije ubwiyongere bw’umubyibuho ukabije na diyabete.Ubushakashatsi bw’abantu n’inyamaswa bwerekanye ko gufata ibiryo byinshi bya fructose bifitanye isano neza no kwiyongera kwa dyslipidemiya, kurwanya insuline, na hypertension.Metabolism ya fructose ibaho cyane cyane mwumwijima kandi fructose itemba itera kwiyongera kwa hepatike triglyceride (hepatike steatose).Ibi bivamo glucose na lipid metabolism no kongera imvugo ya protinflammatory cytokine.Hano twerekana ko fructose ihindura glucose-iterwa no kwerekana imiterere ya acetyl CoA carboxylase ikora (ACC), pSer hormone sensibilité lipase (pSerHSL) hamwe na adipose triglyceride lipase (ATGL) muri hepatike HepG2 cyangwa imico yibanze ya hepatike muri vitro.Ibi byari bifitanye isano no kongera de novo triglyceride synthesis muri vitro na hepatike steatose muri vivo muri fructose- na glucose yagaburiwe nimbeba zisanzwe zigaburirwa imbeba.Ubu bushakashatsi butanga ubumenyi bushya muburyo bukoreshwa na hypertriglyceridemia ya fructose-yunganirwa kandi ikanagaragaza ko gufata fructose ari intego nshya yo kuvura indwara ziterwa na lipide.