Ibicuruzwa

8-Bromo-3-methyl-xanthine, izwi kandi nka 8-BMX, ni uruganda rukomatanya rugizwe nitsinda rya xanthine.Xanthine ni urwego rwibintu bisa na cafine kandi bigira ingaruka kumubiri.Nyamara, 8-BMX byumwihariko ntabwo ikoreshwa cyane cyangwa izwi cyane ugereranije nizindi xantine nka cafine cyangwa theophylline.Bimwe mubintu byambere byakoreshejwe 8-BMX biri mubushakashatsi bwa siyanse nka antagonisti yatoranijwe ya reseptor ya adenosine.Adenosine ni ibintu bisanzwe bibaho mu mubiri bikora nka neuromodulator kandi bigira uruhare mubikorwa bitandukanye bya physiologique, harimo kugenzura ibitotsi, gutwika, n'imikorere yumutima.Muguhagarika reseptor ya adenosine, 8-BMX irashobora guhindura izi nzira kandi igaha abashakashatsi ubumenyi bwingenzi kuruhare rwa adenosine muri sisitemu zitandukanye. Binyuze mubikorwa byayo birwanya reseptor ya adenosine, 8-BMX yakozweho ubushakashatsi ku ngaruka zishobora kugira ku mitsi yo hagati. Sisitemu.Yakoreshejwe mubushakashatsi ku guhangayika, kwiheba, n'indwara zifata ubwonko nka Parkinson na Alzheimer.Muguhagarika reseptor ya adenosine, 8-BMX irashobora guhindura neurotransmission kandi birashobora kugira ingaruka zo kuvura muribi bihe.Icyakora, twakagombye kumenya ko ikoreshwa rya 8-BMX muri ubu bushakashatsi ahanini ari igeragezwa kandi ntirisobanuwe mu mikoreshereze y’amavuriro. Usibye ingaruka zagize kuri sisitemu yo hagati, 8-BMX nayo yakoreshejwe mu bindi bice by’ubushakashatsi. .Kurugero, yakoreshejwe nkigikoresho cyo kwiga uruhare rwa reseptor ya adenosine mumikorere yumutima ndetse no gukora iperereza ku ngaruka ziterwa na antenosine reseptor antagonist ku mutima no ku bihaha.Byongeye kandi, 8-BMX yakozweho ubushakashatsi ku bushobozi ifite mu guhindura ubudahangarwa bw'umubiri no kugabanya umuriro. Ni ngombwa kumenya ko mu gihe 8-BMX yakozweho ubushakashatsi ku mikoreshereze n'ingaruka zayo, uburyo bukoreshwa hanze y’ubushakashatsi bugarukira.Nka sintetike yububiko, ntabwo iboneka mubucuruzi kugirango ikoreshwe muri rusange cyangwa ikoreshwa.Mu nganda zimiti, izindi xanthine nka cafine cyangwa theophylline zikoreshwa cyane kubera imyirondoro yumutekano yashizweho hamwe ningaruka zizwi.Mu gusoza, 8-Bromo-3-methyl-xanthine (8-BMX) ni urugimbu rukoreshwa cyane cyane mubushakashatsi bwa siyanse nka antagonisti yatoranijwe ya reseptor ya adenosine.Yakozweho ubushakashatsi ku ngaruka zishobora kugira kuri sisitemu yo hagati yo hagati, imikorere yumutima nimiyoboro, hamwe no gutwika.Nyamara, ibikorwa byayo bifatika hanze yubushakashatsi bugarukira, kandi izindi xantine nka cafeyine zikoreshwa cyane kandi ziramenyekana.