5-Iodo-2′-deoxycytidine CAS: 54-42-2 98-102% Ifu ya kirisiti yera
| Umubare wa Cataloge | XD90562 |
| izina RY'IGICURUZWA | 5-Iodo-2'-deoxycytidine |
| URUBANZA | 54-42-2 |
| Inzira ya molekulari | C9H11IN2O5 |
| Uburemere bwa molekile | 354.10 |
| Ibisobanuro birambuye | 2 kugeza 8 ° C. |
| Amategeko agenga ibiciro | 29349990 |
Kugaragaza ibicuruzwa
| Kugaragara | Ifu ya kirisiti yera |
| Suzuma | 99% |
| Kuzenguruka byihariye | +25 kugeza +30 |
| Ibyuma biremereye | <0.001% |
| Gutakaza Kuma | <1.0% |
| Ibisigisigi kuri Ignition | <0.3% |
Imiterere ya 3D iteganijwe ya ADN ikubye kabiri ituma ihuza neza nkicyitegererezo cyo hasi-hejuru igishushanyo mbonera cya acide nucleic ikora ishingiye ku mbuga zikora.Hano turasesengura imikoreshereze ya ADN ya 14mer ya ADN nka scafold kugirango ihagarare neza kandi iteganijwe kumikorere ya catalitiki.Urebye uruhare rugaragara rwa groupe ya imidazole ishingiye kuri histidine mu kumenyekanisha poroteyine no mu byabaye muri catalizike, hakozwe iperereza kuri histlexine imwe isa na duplexes.Guhambira histamine kuri C5 ya base ya thymine ukoresheje amide, itanga umwanya uhindagurika wimikorere ya imidazole mumashanyarazi.Imikoranire hagati ya imidazole na duplex ningaruka zayo kuri imidazolium pKaH ikorwaho iperereza hashyirwaho thymine imwe yahinduwe kumyanya ine itandukanye hagati ya 14mer double helix.Hifashishijwe NMR hamwe na molekuliyumu idafite imbaraga, motif yuburyo irimo gushiraho isano ya hydrogène hagati ya imidazole na Hoogste kuruhande rwa base ya guanine yibice bibiri bituranye bya GC.Motif igira uruhare mu gutuza kurwanya ubushyuhe bwa 6 ° C kandi ni urufunguzo rwo guhindura pKaH yitsinda rya imidazolium.Ibintu rusange biranga, ibisabwa hamwe nibisanzwe biranga motif nshya ya pKaH igenga motif irasobanuwe.
