Ibicuruzwa

4-Chloro-2-fluoro-3-mitixyphenylboronic aside ni uruganda rukora imiti rufite uburyo butandukanye muri synthesis organique, chimie chimique, nibikoresho bya siyanse.Bimwe mubintu byambere byakoreshejwe 4-Chloro-2-fluoro-3-mitixyphenylboronic ni mu nzibacyuho icyuma-catalizike ihuza-reaction.Ikora nka acide ya boronic yubaka, itanga uburyo bwo gukora karubone-karubone cyangwa karubone-heteroatom.Kurugero, iyi nteruro irashobora gukoreshwa muri Suzuki-Miyaura ihuza-reaction, aho ikora hamwe na aryl cyangwa vinyl halide munsi ya palladium catalizike kugirango itange ibice bibiri.Izi ngaruka zifatika zikoreshwa cyane muguhuza molekile zigoye, harimo imiti n’ubuhinzi-mwimerere, ndetse no kubaka ibikoresho kama. Ihuriro ridasanzwe ry’amatsinda ya chlorine, fluor, na methoxy mumiterere ya 4-Chloro-2 -fluoro-3-mikorerexyphenylboronic aside ituma synthesis yinkomoko itandukanye ifite imiterere yihariye.Atome ya chlorine irashobora gukora nk'itsinda riyobora inzira yinzibacyuho itangizwa, ikayobora reaction ihitamo ahantu runaka muri molekile.Isimburwa rya Fluorine ritanga lipofilicite yongerewe imbaraga, ishobora kugira ingaruka kumiti ya farumasi ya farumasi no kunoza bioavailable.Itsinda rya methoxy, kurundi ruhande, rishobora gukora nk'itsinda ririnda cyangwa kugira uruhare mu guhindura imiti itandukanye.Mu chimie chimique, 4-Chloro-2-fluoro-3-mitoxyphenylboronic aside n'ibiyikomokaho birashimishije nk'abakandida ibiyobyabwenge.Amatsinda akora nka chlorine na fluor arashobora guhindura imikoranire yikigo hamwe nintego yibinyabuzima no kunoza imiterere ya farumasi.Ikigeretse kuri ibyo, itsinda rya methoxy rirashobora kongera imbaraga za metabolike itajegajega kandi rikagira uruhare muri lipophilicity no kwikemurira ibibazo.Iyi miterere ituma 4-Chloro-2-fluoro-3-mikorerexyphenylboronic aside iba intangiriro yingirakamaro yo guteza imbere imiti mishya yo kuvura mubice nka oncologiya, indwara zanduza, no gutwika.Ikindi kandi, umuvuduko wa aside ya boronic muri 4-Chloro-2-fluoro -3-mikorerexyphenylboronic aside irashobora gutuma habaho ester ya boronate ihamye, yakoreshejwe mugushushanya ibikoresho bifite imiterere yihariye.Ibi bikoresho birashobora kwerekana ibintu byiza, ibikoresho bya elegitoroniki, cyangwa catalitiki, ukurikije imiterere yabyo.Kwinjiza 4-Chloro-2-fluoro-3-mikorerexyphenylboronic aside cyangwa ibiyikomokaho muri ibyo bikoresho birashobora gutanga imikorere yihariye no kuzamura imikorere yabo. Muri make, 4-Chloro-2-fluoro-3-mitoxyphenylboronic aside isanga ikoreshwa mubyiciro bitandukanye. bitewe na chimie itandukanye hamwe nubushobozi bwo gukora molekile ikora nibikoresho.Uruhare rwarwo mu nzibacyuho-iterwa no guhuza reaction, ihujwe nimiterere yihariye yimiryango ikora, bituma iba igikoresho cyingirakamaro muri synthesis organique na chimie chimique.Byongeye kandi, acide ya boronic ituma habaho ester ya boronate, igira uruhare mugutezimbere ibikoresho bigezweho bifite imiterere yihariye.