Ibicuruzwa

4- (4-Fluorophenyl) -6-isopropyl-2 - .Imiterere yihariye hamwe nitsinda ryimikorere bituma iba umukandida ushimishije kuvumbura no guteza imbere ibiyobyabwenge.Bimwe mubishobora gukoresha Z6 ni nka anti-inflammatory.Gutwika bigira uruhare mu ndwara nyinshi, zirimo rubagimpande ya rubagimpande, indwara zifata amara, na asima.Itsinda rya Z6 ryasimbuwe na fenil hamwe na pyrimidine yibanze bituma bikwiranye nintego zihariye zigira uruhare mugikorwa cyo gutwika, bikaba byaviramo iterambere ryimiti igabanya ubukana.Z6 nayo isezeranya nkumuti wa virusi.Indwara ziterwa na virusi zikomeje kuba ikibazo cy’ubuzima ku isi, kandi hakenewe ubuvuzi bushya kandi bunoze bwo kuvura virusi.Kubaho kwitsinda rya isopropyl muri Z6 byongera imiterere ya hydrophobique, bigatuma ishobora kwinjira muri virusi kandi ikabuza kwigana virusi.Imiterere yimiterere yayo irashobora kunozwa kugirango yibasire cyane imisemburo ya virusi cyangwa proteyine, biganisha ku iterambere ryimiti ikomeye ya virusi. Byongeye kandi, Z6 irashobora kuba ifite imiti ivura kanseri.Itsinda rya fluoro ryasimbuwe na fenyl hamwe na pyrimidine yibanze bikunze kuboneka hamwe nibikorwa bya anticancer.Muguhindura imiterere ya Z6, birashoboka ko habaho inkomoko yibasiye ingirabuzimafatizo za kanseri, bikabuza gukura kwabo no gutera apoptose mugihe wirinze ingirabuzimafatizo nziza.Urusobekerane rukomeye kandi ruhamye narwo rushobora kunozwa kugirango rutezimbere kandi rugabanye ingaruka zishobora kubaho.Ikindi kandi, Z6 irashobora gukoreshwa nkintangiriro yo guhuza amasomero mato mato mato cyangwa scafolds.Itanga guhinduka kugirango ihindurwe kandi itezimbere, itanga ubushakashatsi ku mibanire yimirimo-ibikorwa no kumenya ibice byayobora kugirango biteze imbere.Mu ncamake, Z6 nuruvange rutanga ikizere hamwe nibishobora gukoreshwa murwego rwa farumasi.Imiterere yimiterere hamwe nitsinda ryimikorere bituma bikwiranye nuburyo butandukanye bwo kuvura, harimo kurwanya anti-inflammatory, antiviral, na anticancer.Hamwe nubushakashatsi niterambere, Z6 nibiyikomokaho bifite ubushobozi bwo gutanga umusanzu ukomeye mubuvumbuzi bwibiyobyabwenge kandi bikagira uruhare mugutezimbere ubuvuzi bushya kandi bwiza.