Ibicuruzwa

. (3R, 4S, 5R, 6R) -1 ya molekile igoye.Urusobekerane rufite imbuga nyinshi zidasanzwe zishobora guhinduka mumatsinda atandukanye.TBDMS (tert-butyldimethylsilyl) irinda itsinda rihari muri molekile ritanga ituze kandi ryemerera guhitamo guhitamo amatsinda yihariye akora.Ubu buryo butandukanye butuma tetrahydro irinzwe na TBDMS-2H-pyran-2-imwe hagati yigihe cyagaciro muguhuza ibicuruzwa karemano, imiti, nindi miti myiza.Ubundi buryo bukomeye bwo gukoresha tetrahydro irinzwe na TBDMS-2H-pyran-2-imwe ni yo uruhare nkitsinda ririnda alcool na amine muri synthesis.Itsinda rya TBDMS rirashobora kongerwaho guhitamo mumatsinda ya hydroxyl cyangwa amino, kubitwikira neza mugihe cyintambwe zitandukanye.Ubu burinzi burinda impande-zidashaka kandi zemeza ko impinduka zifuzwa zibaho kurubuga rwifuzwa.Iyo ibyifuzo byifuzwa bimaze kurangira, itsinda rya TBDMS rirashobora gukurwaho byoroshye, bikerekana hydroxyl cyangwa amatsinda yumwimerere bitagize ingaruka kubindi bikorwa muri molekile.TBDMS irinzwe na tetrahydro-2H-pyran-2-imwe nayo isanga gusaba nkumukozi urinda karubone.Iremera uburyo bwo kurinda amatsinda ya hydroxyl muri molekile yisukari mugihe cya glycosylation reaction, bigafasha synthesis ya glycans igoye na glycoside.Izi ngamba zo gukingira ni ingenzi cyane muri chimie ya karubone, aho amatsinda menshi ya hydroxyl ahari kandi hakenewe regioselectivite yihariye.Ikindi kandi, TBDMS irinzwe na tetrahydro-2H-pyran-2-imwe ikoreshwa mugutegura polymers ikora.Urusobekerane rushobora kwinjizwa muburyo bwa polymer, rutanga imbuga zifatika kugirango zihindurwe kandi zihuze reaction.Ibi bifasha gukora ibikoresho bya polymer bifite imiterere nuburyo bukora, nko gutezimbere umutekano, biocompatibilité, no kugenzura ibiyobyabwenge. Mugusoza, (3R, 4S, 5R, 6R) -3,4,5-tris (triMethylsilyloxy) -6 - (. .Ubushobozi bwayo bwo guhitamo kurinda amatsinda akora no koroshya ihinduka ryimikorere ya molekile bituma iba igikoresho cyagaciro mubijyanye na chimie.Gukomeza ubushakashatsi nubushakashatsi bwakoreshejwe birashobora kuvumbura ubundi buryo bukoreshwa kandi bikagira uruhare mu iterambere muri chimie yubumenyi nubumenyi bwibintu.