3,3 ′, 5,5′-Tetramethyl- [1,1'-biphenyl] -4,4′-diamine Cas: 54827-17-7 99%
Umubare wa Cataloge | XD90518 |
izina RY'IGICURUZWA | 3,3 ', 5,5'-Tetramethyl- [1,1'-biphenyl] -4,4'-diamine |
URUBANZA | 54827-17-7 |
Inzira ya molekulari | C16H20N2 |
Uburemere bwa molekile | 240.34 |
Ibisobanuro birambuye | 2 kugeza 8 ° C. |
Amategeko agenga ibiciro | 29215990 |
Kugaragaza ibicuruzwa
Kugaragara | Cyera, cyera kugeza cyera cyangwa ifu yumuhondo |
Suzuma | > 99% |
Gutakaza Kuma | <2.0% |
Kubushakashatsi ukoreshe gusa, ntabwo ari ugukoresha abantu | gukoresha ubushakashatsi gusa, ntabwo ari ugukoresha abantu |
Uburozi bwa Ricin (RT) nuburozi bwa kabiri bwica cyane buzwi;yagenwe na CDC nkumukozi watoranije.RT ikorwa nigihingwa cyibishyimbo;toni zigera ku 50.000 za RT zikorwa buri mwaka nkibikomoka kuri peteroli.RT ifite subunits ebyiri, ribotoxic Urunigi (RTA) hamwe na galaktose ihuza B (RTB).RT ihuza ingirangingo zose z’inyamabere kandi zimaze kwinjizwamo, RTA imwe itanga catisale idakora ribosomes zose muri selile.Ikoreshwa nka aerosol, RT itera kwangirika kw ibihaha byihuse na fibrosis ikurikirwa nurupfu.Nta nkingo zemewe n’ubuyobozi bw’ibiribwa n’ibiyobyabwenge kandi kuvura bigira akamaro gusa mu masaha ya mbere nyuma yo guhura.Twashyizeho urukingo rwa Rombombant RTA rufite mutation ebyiri V76M / Y80A (RiVax).Poroteyine igaragara muri Escherichia coli kandi ni nontoxic na immunogenic mu mbeba, inkwavu, n'abantu.Iyo imbeba zakingiwe zirwanya inshinge, aerosolize, cyangwa gutangwa mu kanwa (gavaged) RT, birarindwa rwose.Ubu twateguye uburyo bwa termostable, aluminium-adjuvant irimo formulaire ya RiVax hanyuma tuyigerageza muri rhesus macaques.Nyuma yo guterwa inshuro eshatu, inyamaswa zakoze antibodiyide zabarindaga burundu igipimo cyica cya aerosolize RT.Izi antibodies zatesheje agaciro RT kandi zirushanijwe muburyo butandukanye hamwe nitsinda ryo kutabogama no kutabogama antibodiyite yimbeba monoclonal izwiho kumenya epitopes yihariye kuri RTA kavukire.Umwirondoro wa antibody wavuyemo urashobora kwerekana umukono wikingira.Icyangombwa, umukono umwe wagaragaye ukoresheje sera yabantu bakingiwe na RiVax.