3-Acide Quinolinecarboxylic, 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo- CAS: 117528-65-1
Umubare wa Cataloge | XD93405 |
izina RY'IGICURUZWA | 3-Acide Quinolinecarboxylic, 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo- |
URUBANZA | 117528-65-1 |
Imiterere ya molekularila | C14H8ClFN2O3 |
Uburemere bwa molekile | 306.68 |
Ibisobanuro birambuye | Ibidukikije |
Kugaragaza ibicuruzwa
Kugaragara | Ifu yera |
Assay | 99% min |
3-Acide Quinolinecarboxylic, 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, izwi kandi nka levofloxacin, ni antibiyotike yagutse ikoreshwa cyane mu kuvura y'indwara zitandukanye.Ni mu cyiciro cya fluoroquinolone ya antibiyotike kandi ikagaragaza ibikorwa bya mikorobe ikomeye irwanya bagiteri zombi zitwa Gram-positif na Gram-negative.Levofloxacin ikoreshwa cyane mu gucunga indwara zandurira mu myanya y'ubuhumekero nka bronchite na pnewoniya, ndetse n'indwara zanduza inkari, uruhu na kwandura imyenda yoroheje, na prostatite ya bagiteri.Uburyo bwibikorwa byabwo bikubiyemo guhagarika bagiteri ADN ya gyrase na topoisomerase IV enzymes, zikenerwa mugusubiramo ADN, gusana, no kwiyubaka muri bagiteri.Mu kwivanga niyi misemburo, levofloxacin ihagarika synthesis ya ADN ya bagiteri, biganisha ku rupfu rwa bagiteri.Levofloxacin yinjizwa neza mu kanwa kandi ikerekana ingirabuzimafatizo nziza yinjira, bigatuma ishobora kugera cyane aho yanduye.Uyu mutungo ugira uruhare runini mu kurwanya virusi zitandukanye, harimo nizindi zirwanya antibiyotike.Byongeye kandi, levofloxacin yerekana ubuzima burebure bwigihe kirekire, butanga inshuro imwe kumunsi, byongera kubahiriza abarwayi no kuborohereza. Usibye kuba ikoreshwa mukuvura indwara ziterwa na bagiteri, levofloxacin yanagaragaje ibikorwa birwanya indwara zidasanzwe nka Mycoplasma pneumoniae na Legionella pneumophila.Ibi bituma ihitamo neza kuvura indwara zidasanzwe z'umusonga.Byongeye kandi, levofloxacin yasanze ifite akamaro mu kurandura Helicobacter pylori, bagiteri ifitanye isano no gukura kwa gastrite na ibisebe bya peptike.Nyamara, ni ngombwa kumenya ko gukoresha levofloxacine bigomba gukorwa ubwitonzi, urebye ubushobozi bushobora kubaho ingaruka mbi no guteza imbere antibiyotike.Levofloxacin yagiye ifitanye isano n'ingaruka nko kugira isesemi, impiswi, kubabara umutwe, no kuzunguruka.Ntigomba gukoreshwa mubantu bafite hyperensitivite izwi cyane kuri fluoroquinolone cyangwa mubantu bamwe barwayi barwaye nkabagore batwite, ababyeyi bonsa, nabana bari munsi yimyaka 18.Musoza, 3-Quinolinecarboxylic aside, 7-chloro-8-cyano-1 -cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, cyangwa levofloxacin, ni antibiyotike ikomeye kandi ikoreshwa cyane mu kuvura indwara ziterwa na bagiteri.Igikorwa cyacyo kigari, ibikorwa byiza byinjira, hamwe nuburyo bworoshye bwo gufata imiti bituma habaho uburyo bwiza bwo kuvura.Icyakora, hagomba kwitonderwa mugukoresha, harebwa ingaruka zishobora guterwa no kurwanya antibiyotike.