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Ibicuruzwa

2- (3,5-Dimethyl-4- (2-
  • 2- (3,5-Dimethyl-4- (2-

2- (3,5-Dimethyl-4- (2-

Ibisobanuro bigufi:

Umubare wa Cataloge: XD90961
Cas: 1044871-04-6
Inzira ya molekulari: C24H29N3O4
Uburemere bwa molekile: 423.5
Kuboneka: Mububiko
Igiciro:  
Gutegura:  
Igipapuro kinini: Saba Amagambo

 


Ibicuruzwa birambuye

Ibicuruzwa

Umubare wa Cataloge XD90961
izina RY'IGICURUZWA 2- (3,5-Dimethyl-4- (2- (pyrrolidin-1-yl) ethoxy) fenyl) -5,7-dimethoxyquinazolin-4 (3H) -umuntu

URUBANZA

 1044871-04-6

Inzira ya molekulari

 C24H29N3O4

Uburemere bwa molekile

 423.5
Ibisobanuro birambuye  
Amategeko agenga ibiciro  

 

Kugaragaza ibicuruzwa

Kugaragara  
Suzuma  
Bingingo ya peteroli 612.6 ± 65.0 ° C (Biteganijwe)
Ubucucike 1.25 ± 0.1 g / cm3 (Biteganijwe)
Coefficient ya acide (pKa) 9.54 ± 0.20 (Biteganijwe)

 

RVX-297 nimbaraga zikomeye, mumvugo ikora BET inhibitor ihitamo BD2.IC50s ya RVX-297 kuri BRD2 (BD2), BRD3 (BD2), na BRD4 (BD2) yari 0.08, 0.05, na 0.02 μM.RVX-297 ibuza kwerekana ingirabuzimafatizo zitandukanye.Ingaruka za RVX-297 muburyo bwa preclinical of acute inflammation and autoimmunity.

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