1,1-Cyclobutanedicarboxylatodiammineplatinum (II) Cas: 41575-94-4
Umubare wa Cataloge | XD90684 |
izina RY'IGICURUZWA | 1,1-Cyclobutanedicarboxylatodiammineplatinum (II) |
URUBANZA | 41575-94-4 |
Inzira ya molekulari | C6H12N2O4Pt |
Uburemere bwa molekile | 371.25 |
Ibisobanuro birambuye | 2-8 ° C. |
Amategeko agenga ibiciro | 28439090 |
Kugaragaza ibicuruzwa
Kugaragara | Ifu yera kugeza yera |
Suzuma | 99% |
Amazi | ≤0.5% |
Gutakaza Kuma | ≤0.5% |
Chloride | ≤100ppm |
Ibintu bifitanye isano | ≤0.25% |
Umwanda uwo ariwo wose udasobanutse | ≤ 0.1% |
Ibindi byose byanduye | ≤0.5% |
1,1-Acide Cyclobutanedicarboxylic | ≤ 0.5% |
Igisekuru cya kabiri cya platine igoye imiti igabanya ubukana.Imikorere ya antitumor hamwe nibikorwa bya antitumor bisa nibya cisplatine, ariko gukemura amazi ni byiza kuruta ibya cisplatine, kandi uburozi bwimpyiko nabwo buri hasi.Ifite ingaruka nziza zo kuvura kanseri y'ibihaha ntoya, kanseri yintanga, kanseri yo mu mutwe no mu ijosi karcinoma, ikibyimba cya testicular, lymphoma mbi, n'ibindi. Irashobora kandi gukoreshwa kuri kanseri y'inkondo y'umura, kanseri y'uruhago, n'ibindi.
Igisekuru cya kabiri imiti igabanya ubukana bwa platine ifite ahanini imirimo imwe kandi ikoresha nka cisplatine.Irakora cyane kuruta cisplatine kubibyimba bimwe na bimwe, kandi irakomeye kuruta cisplatine nka radiosensitizer mugihe cya hypoxic.Ahanini ikoreshwa kuri kanseri yintanga, kanseri yintangangore, kanseri yibihaha na kanseri yo mumutwe no mu ijosi.
Carboplatine ni imiti igabanya ubukana bwa platine yangiza ADN yangiza ADN ikora imitsi ihuza ibisigazwa bya guanine.Ingaruka ya antitumor yiyi miti igerwaho no gutakaza ibikorwa byo gusana ADN bidahuye (urukingo rwa MMR) no kwinjiza urupfu rwa selile;