Ibicuruzwa

1-Methyl-4-pyrazole boronic acide pinacol ester nuruvange rufite uburyo bwinshi bwo gukoresha, cyane cyane mubijyanye na synthesis organique.Imiterere yihariye hamwe na reactivite bituma igira agaciro mubitekerezo bitandukanye bya chimique kandi nkibice byubaka kugirango habeho synthesis ya molekile zigoye.Bimwe mubintu byingenzi byakoreshejwe 1-Methyl-4-pyrazole boronic acide pinacol ester iri mukurema karubone-karubone cyangwa karubone-heteroatom.Itsinda rya aside ya boronic muri molekile irashobora guhura na Suzuki-Miyaura kwambukiranya, bigafasha guhuza 1-methyl-4-pyrazole moiety mubindi bice cyangwa amatsinda akora.Iyi reaction ituma abahanga mu bya shimi bakora ibinyabuzima bigoye hamwe nuburyo buboneye. Byongeye kandi, itsinda rya pinacol ester muri molekile ritanga ituze kandi ririnda imikorere ya acide boronic mugihe cyo kwitwara gutandukanye.Iri tsinda ririnda rishobora gukurwaho byoroshye mugihe cyoroheje, bityo bikagaragaza itsinda rya aside ya boronic kugirango irusheho guhinduka.Kubera iyo mpamvu, 1-Methyl-4-pyrazole boronic aside pinacol ester ikora nkumuhuza uhuza muguhuza imiti, imiti y’ubuhinzi, n’indi miti myiza.Mu nganda zimiti, uru ruganda rushobora gukoreshwa nkibice byingenzi byubaka kugirango bihuze abakandida ibiyobyabwenge.Ukoresheje 1-Methyl-4-pyrazole boronic acide pinacol ester nkibikoresho byo gutangira, abahanga mu bya shimi barashobora kwinjiza 1-methyl-4-pyrazole moile muri molekile yintego, bagatanga ibintu byihariye cyangwa imikorere.Ibivanze bivamo bishobora kwerekana ibikorwa byibinyabuzima byongerewe imbaraga, kunoza imiti ya farumasi, cyangwa kugabanya uburozi.Ikindi kandi, 1-Methyl-4-pyrazole boronic acide pinacol ester ifite agaciro mubumenyi bwibintu na catalizike.Irashobora gukora nka ligand, igahuza ibyuma bitanga ibyuma kandi ikagira uruhare mubikorwa bitandukanye bya catalitiki.Itsinda rya acide ya boronic irashobora gukora ibice hamwe nibyuma byinzibacyuho, bigatuma habaho gukora imigozi ya CH cyangwa catalizike yo guhuza ibitekerezo.Iyi mico ituma igira akamaro muguhuza ibikoresho bikora cyangwa guteza imbere sisitemu nshya ya catalitiki.Mu ncamake, 1-Methyl-4-pyrazole boronic acide pinacol ester nuruvange rwinshi rufite akamaro gakomeye muri synthesis organique, farumasi, siyanse yubumenyi, na isesengura.Imikorere ya acide ya boronic hamwe nitsinda rya pinacol ester ituma bigira akamaro muburyo bwa karubone-karubone cyangwa karubone-heteroatom ihuza imbaraga, bigafasha kubaka molekile zigoye.Porogaramu zayo zikubiyemo inganda zitandukanye, zirimo guhuza imiti, guteza imbere ibikoresho bikora, no guteza imbere sisitemu ya catalitiki.Guhindura byinshi hamwe na reaction ya 1-Methyl-4-pyrazole boronic acide pinacol ester bituma iba igikoresho cyagaciro kubashinzwe imiti bakora kuri synthesis yibintu bishya no gutegura ibisubizo bishya.