Ibicuruzwa

Iperereza rya phytochemiki ku gihingwa cyose cya Lepisorus contortus (Christ) Ching ryatumye habaho akato ka glycoside eshanu nshya ya fenylethanoide (1-5), buri imwe irimo itsinda rya cafeyl, glycoside nshya ya flavonoide (10), hamwe n’ibintu 14 bizwi (6-9) na 11-15, acide syringic, aside vanillic, aside phloretike, diplomopterol, na β-sitosterole).Ngiyo raporo yambere ya fenylethanoid glycoside yo mumuryango Polypodiaceae.Ibicuruzwa 1-15 byasuzumwe ubushobozi bwabo bwa kanseri ya chemopreventive hashingiwe ku bushobozi bafite bwo kubuza ibibyimba biterwa na alpha (TNF-α) -byakozwe na NF-κB, umusaruro wa nitric oxyde (OYA), hamwe na aromatase, kugabanya quinone 2 (QR-2 ), n'ibikorwa bya COX-1 / -2.Quercetin-3-O-β-d-glucoside (15) yerekanye ko itabujije QR2 ifite agaciro ka IC (50) ifite agaciro ka 3.84 μM, yemeje kaempferol / quercetin glycoside nkibintu bifatika bibuza QR2.Urwo ruganda rwerekanye kandi ibikorwa bya NF-κB bifite IC (50) bifite agaciro ka 33,6 μM.Hiyongereyeho, ibice 1, 2, 4, na 6 byerekanaga ibikorwa bya omatase hamwe na IC (50) bifite agaciro ka 30.7, 32.3, 26.8, na 35.3 μM.