γ-L-Glutamyl-3-carboxy-4-nitroanilide, umunyu wa monoammonium Cas: 63699-78-5 Ifu ya microcrystalline yumuhondo yoroheje
| Umubare wa Cataloge | XD90183 |
| izina RY'IGICURUZWA | γ-L-Glutamyl-3-carboxy-4-nitroanilide, umunyu wa monoammonium |
| URUBANZA | 63699-78-5 |
| Inzira ya molekulari | C12H12N3O7-.H4N + |
| Uburemere bwa molekile | 328.27 |
| Ibisobanuro birambuye | Ibidukikije |
Kugaragaza ibicuruzwa
| Kugaragara | Ifu yumuhondo microcrystalline |
| Assay | 99% |
| Ingingo yo gushonga | 187ºC ± 2.0ºC |
| Ingingo yo guteka | 718.3 ° C kuri 760 mmHg |
| Ingingo ya Flash | 368.5 ° C. |
| Gukemura | H2O: 100 mg / mL, bisobanutse, umuhondo-icyatsi |
Hakozwe iperereza ku mikorere ya serumu yumuntu gamma-glutamyltransferase (EC 2.3.2.2), hifashishijwe glycylglycine nka substrate ya gamma-glutamyl na gamma-glutamyl-4-nitroanilide hamwe na karubasi ikomokaho, gamma-glutamyl-3-carboxy-4 -nitroanilide, nkumuterankunga.Ibibaho icyarimwe byombi bya gamma-glutamyltransfer na autotransfer byashizweho no kumanuka impapuro chromatografiya.Ibipimo bihoraho-byombi byuzuzanya byemeza ko uburyo bwa enzyme budakurikiraho (ping-pong bi-bi).Kubuzwa n’umuterankunga ntiwabonetse, kandi kubuzwa na glycylglycine byagaragaye gusa ku kwibanda hejuru y’inyungu z’ubuvuzi.Kinetic constants yabonetse kubisesenguye bidasubirwaho isesengura ryambere ryihuta ryakoreshejwe kugirango hamenyekane reagent substrate yibanze kugirango isuzume iyi misemburo.Ubushakashatsi bwakoresheje mmol 4 ya gamma-glutamyl-3-carboxy-4-nitroanilide na mmol 100 ya glycylglycine kuri litiro byatanze ibikorwa bihwanye nababashakashatsi bakoresheje mmol 4 za gamma-glutamyl-4-nitroanilide na 40 mmol ya glycylglycine kuri litiro.Iyegeranya ryumuterankunga wa carboxy na glycylglycine naryo "rihendutse" kandi ntagaragaza ibibazo byikurikiranabikorwa iyo bikoreshejwe.
